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CD28 Antikörper (C-Term)

Name: CD28 Antikörper (C-Term)
SKU: ABIN6260603
Price: 720 EUR
Availability: InStock

CD28 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis of extracts from mouse spleen, using CD28 Antibody. (CD28 Antikörper (C-Term))

ABIN6266446 at 1/100 staining Human thyroid cancer tissue by IHC-P. (CD28 Antikörper (C-Term))

IHC

Western blot analysis of extracts from HepG2, using CD28 Antibody. (CD28 Antikörper (C-Term))

3 Abbildungen

Produktnummer ABIN6260603

Datenblatt (PDF)

Target Alle CD28 Antikörper anzeigen

CD28
Bindungsspezifität
16

15

8

5

4

3

3

2

2

1

1

1

1

1

1

1

1

1
C-Term
Reaktivität
172

126

52

37

23

16

12

12

7

7

6

6

2

1

1

1

1

1
Human, Maus, Ratte
Wirt
155

67

33

18

12

3

2
Kaninchen
Passende Sekundärantikörper
Klonalität
224

60

3
Polyklonal
Konjugat
107

33

30

21

16

6

6

6

5

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
Dieser CD28 Antikörper ist unkonjugiert
Applikation
227

87

59

48

37

36

33

26

23

17

13

7

7

6

6

5

5

4

4

4

4

3

2

2

2

2

2

1

1

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität

CD28 Antibody detects endogenous levels of total CD28.

Homologie

Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen

A synthesized peptide derived from human CD28, corresponding to a region within C-terminal amino acids.

Isotyp

IgG

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anti-CD28 (CD28) (AA 1-120) antibody
CD28 Reaktivität: Human, Maus, Ratte FACS, WB, ELISA, IHC (fro), IF (p), IHC (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated

anti-CD28 (CD28) antibody
CD28 Reaktivität: Human, Non-Human Primate FACS, WB, IP, IHC (fro), ICC Wirt: Maus Monoclonal CD28-2 unconjugated

anti-CD28 (CD28) antibody (FITC)
CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 FITC

anti-CD28 (CD28) antibody
CD28 Reaktivität: Human, Non-Human Primate FACS, WB, IP, Func, IHC (fro), ICC Wirt: Maus Monoclonal CD28-2 unconjugated

anti-CD28 (CD28) (AA 19-152) antibody
CD28 Reaktivität: Human FACS, ELISA Wirt: Kaninchen Monoclonal DM61 unconjugated Recombinant Antibody

anti-CD28 (CD28) antibody
CD28 Reaktivität: Ratte FACS, IP Wirt: Maus Monoclonal JJ319 unconjugated

anti-CD28 (CD28) antibody (PE)
CD28 Reaktivität: Ratte FACS Wirt: Maus Monoclonal JJ319 PE

anti-CD28 (CD28) antibody (PerCP)
CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 PerCP

anti-CD28 (CD28) antibody (APC)
CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 APC

anti-CD28 (CD28) antibody (PE)
CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 PE

Applikationshinweise

WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol. .

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit

12 months
Target

CD28

Andere Bezeichnung

CD28 (CD28 Produkte)

Hintergrund

Description: Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation (PubMed:8617933). Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells (PubMed:15067037).
Gene: CD28

Molekulargewicht

25 kDa

Gen-ID

940

UniProt

P10747

Pathways

T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response