CDK13 Antikörper (Internal Region)

Produktnummer ABIN6260604

Produktdetails anti-CDK13 Antikörper

Target: CDK13 (Cyclin-Dependent Kinase 13 (CDK13))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK13 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: CD2L5 Antibody detects endogenous levels of total CD2L5.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CD2L5, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CDK13

Target: CDK13 (Cyclin-Dependent Kinase 13 (CDK13))

Andere Bezeichnung: CDK13 (CDK13 Produkte)

Synonyme: CDC2L5 antikoerper, cdc2l5 antikoerper, wu:fe16d10 antikoerper, wu:fi49c05 antikoerper, CDC2L antikoerper, CHED antikoerper, hCDK13 antikoerper, 2310015O17Rik antikoerper, Cdc2l5 antikoerper, cyclin dependent kinase 13 antikoerper, cyclin-dependent kinase 13 antikoerper, CDK13 antikoerper, cdk13 antikoerper, Cdk13 antikoerper

Hintergrund:

Description: Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at 'Lys-50' and 'Lys-51', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef.

Gene: CDK13

Molekulargewicht: 165 kDa

Gen-ID: 8621

UniProt: Q14004