CD40 Ligand Antikörper (Internal Region)
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- Target Alle CD40 Ligand (CD40LG) Antikörper anzeigen
- CD40 Ligand (CD40LG)
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CD40 Ligand Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- Spezifität
- CD40L Antibody detects endogenous levels of total CD40L.
- Homologie
- Bovine,Sheep,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CD40L, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product CD40LG Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000, IF/ICC 1:200-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- CD40 Ligand (CD40LG)
- Andere Bezeichnung
- CD40LG (CD40LG Produkte)
- Synonyme
- CD154 antikoerper, cd40l antikoerper, CD40L antikoerper, HIGM1 antikoerper, IGM antikoerper, IMD3 antikoerper, T-BAM antikoerper, TNFSF5 antikoerper, TRAP antikoerper, gp39 antikoerper, hCD40L antikoerper, CD40-L antikoerper, Cd40l antikoerper, Ly-62 antikoerper, Ly62 antikoerper, Tnfsf5 antikoerper, CD40 ligand antikoerper, TNF superfamily member 5 antikoerper, CD40LG antikoerper, cd40l antikoerper, Cd40lg antikoerper
- Hintergrund
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Description: Cytokine that binds to CD40/TNFRSF5 (PubMed:1280226). Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (PubMed:8617933). Induces the activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells. Induces tyrosine phosphorylation of isoform 3 of CD28 (PubMed:15067037). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching (By similarity).
Gene: CD40LG
- Molekulargewicht
- 36 kDa
- Gen-ID
- 959
- UniProt
- P29965
- Pathways
- NF-kappaB Signalweg, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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