CDK3 Antikörper (C-Term)
(1 reference)-
- Target Alle CDK3 Antikörper anzeigen
- CDK3 (Cyclin-Dependent Kinase 3 (CDK3))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CDK3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- CDK3 Antibody detects endogenous levels of total CDK3.
- Homologie
- Pig,Bovine,Sheep,Rabbit
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CDK3, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product CDK3 Primärantikörper
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anti-Cyclin-Dependent Kinase 3 (CDK3) (AA 206-305) antibody
CDK3 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 3C12 unconjugated
anti-Cyclin-Dependent Kinase 3 (CDK3) (AA 4-38), (N-Term) antibodyCDK3 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB15488 unconjugated
anti-Cyclin-Dependent Kinase 3 (CDK3) (AA 249-277), (C-Term) antibodyCDK3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB34458 unconjugated
anti-Cyclin-Dependent Kinase 3 (CDK3) (AA 1-305) antibodyCDK3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 3 (CDK3) (AA 220-297) antibodyCDK3 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 3 (CDK3) (C-Term) antibodyCDK3 Reaktivität: Human, Rind (Kuh), Hund, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 3 (CDK3) (C-Term) antibodyCDK3 Reaktivität: Human, Maus, Rind (Kuh), Hund WB Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 3 (CDK3) (C-Term) antibodyCDK3 Reaktivität: Human, Maus, Rind (Kuh), Hund, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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-
: "CDK3 is a major target of miR-150 in cell proliferation and anti-cancer effect." in: Experimental and molecular pathology, Vol. 102, Issue 2, pp. 181-190, (2017) (PubMed).
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: "CDK3 is a major target of miR-150 in cell proliferation and anti-cancer effect." in: Experimental and molecular pathology, Vol. 102, Issue 2, pp. 181-190, (2017) (PubMed).
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- Target
- CDK3 (Cyclin-Dependent Kinase 3 (CDK3))
- Andere Bezeichnung
- CDK3 (CDK3 Produkte)
- Synonyme
- 2310050O10Rik antikoerper, Cdk3 antikoerper, cyclin dependent kinase 3 antikoerper, cyclin-dependent kinase 3 antikoerper, cyclin-dependent kinase 3, pseudogene antikoerper, CDK3 antikoerper, cgd3_1510 antikoerper, Chro.30182 antikoerper, Cdk3-ps antikoerper
- Hintergrund
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Description: Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle, involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1-independent manner.
Gene: CDK3
- Molekulargewicht
- 35 kDa
- Gen-ID
- 1018
- UniProt
- Q00526
- Pathways
- Zellzyklus
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