Centriolin Antikörper
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- Target Alle Centriolin (CNTRL) Antikörper anzeigen
- Centriolin (CNTRL)
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Centriolin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Spezifität
- CEP110 Antibody detects endogenous levels of total CEP110
- Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CEP110
- Isotyp
- IgG
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- Applikationshinweise
- WB 1:1000-3000 IHC 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- Haltbarkeit
- 12 months
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- Target
- Centriolin (CNTRL)
- Andere Bezeichnung
- CEP110 (CNTRL Produkte)
- Synonyme
- CEP1 antikoerper, CEP110 antikoerper, FAN antikoerper, bA165P4.1 antikoerper, Cep1 antikoerper, Cep110 antikoerper, 6720467O09Rik antikoerper, AA968343 antikoerper, Cntrl antikoerper, IB3/5 antikoerper, Ma2a8 antikoerper, b2b1468Clo antikoerper, centriolin antikoerper, CNTRL antikoerper, Cntrl antikoerper
- Hintergrund
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Description: Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425).
Gene: CCP110
- Molekulargewicht
- 113kDa
- Gen-ID
- 9738
- UniProt
- O43303
- Pathways
- M Phase, SARS-CoV-2 Protein Interaktom
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