CISD2 Antikörper (Internal Region)
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- Target Alle CISD2 Antikörper anzeigen
- CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CISD2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Spezifität
- CISD2 Antibody detects endogenous levels of total CISD2.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CISD2, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product CISD2 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))
- Andere Bezeichnung
- CISD2 (CISD2 Produkte)
- Synonyme
- ERIS antikoerper, Miner1 antikoerper, NAF-1 antikoerper, WFS2 antikoerper, ZCD2 antikoerper, 1500009M05Rik antikoerper, 1500026J14Rik antikoerper, 1500031D15Rik antikoerper, AI848398 antikoerper, B630006A20Rik antikoerper, Noxp70 antikoerper, Zcd2 antikoerper, RGD1566242 antikoerper, zgc:64148 antikoerper, eris antikoerper, miner1 antikoerper, wfs2 antikoerper, zcd2 antikoerper, cisd2 antikoerper, BcDNA:RE49709 antikoerper, Dmel\\CG1458 antikoerper, CDGSH iron sulfur domain 2 antikoerper, CDGSH iron sulfur domain 2 L homeolog antikoerper, CDGSH iron sulfur domain 2 S homeolog antikoerper, CISD2 antikoerper, Cisd2 antikoerper, cisd2 antikoerper, cisd2.L antikoerper, cisd2.S antikoerper
- Hintergrund
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Description: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca2+ stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.
Gene: CISD2
- Molekulargewicht
- 13-15 kDa
- Gen-ID
- 493856
- UniProt
- Q8N5K1
- Pathways
- Activation of Innate immune Response
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