CLDN10 Antikörper (C-Term)

Produktnummer ABIN6260861

Produktdetails anti-CLDN10 Antikörper

Target: CLDN10 (Claudin 10 (CLDN10))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLDN10 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Claudin 10 Antibody detects endogenous levels of total Claudin 10.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Claudin 10, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CLDN10

Target: CLDN10 (Claudin 10 (CLDN10))

Andere Bezeichnung: CLDN10 (CLDN10 Produkte)

Synonyme: si:busm1-52i16.3 antikoerper, si:dz52i16.3 antikoerper, CLDN10 antikoerper, DKFZp469F1626 antikoerper, CPETRL3 antikoerper, OSP-L antikoerper, 6720456I16Rik antikoerper, Cldn10a antikoerper, Cldn10b antikoerper, D14Ertd728e antikoerper, claudin 10a antikoerper, claudin 10 antikoerper, cldn10a antikoerper, CLDN10 antikoerper, Cldn10 antikoerper

Hintergrund:

Description: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in the regulation of paracellular epithelia permeability to ions in multiple organs. It acts as a paracellular ion channel probably forming permselective pores, isoform 1 appears to create pores preferentially permeable to cations and isoform 2 for anions. In sweat glands and in the thick ascending limb (TAL) of Henle's loop in kidney, it controls paracellular sodium permeability which is essential for proper sweat production and renal function (PubMed:19383724, PubMed:28771254, PubMed:28686597).

Gene: CLDN10

Molekulargewicht: 25kDa

Gen-ID: 9071

UniProt: P78369

Pathways: Hepatitis C