Calsyntenin 1 Antikörper (C-Term)
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- Target Alle Calsyntenin 1 (CLSTN1) Antikörper anzeigen
- Calsyntenin 1 (CLSTN1)
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Calsyntenin 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- CLSTN1 Antibody detects endogenous levels of total CLSTN1.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CLSTN1, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product CLSTN1 Primärantikörper
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anti-Calsyntenin 1 (CLSTN1) (AA 1-971) antibody
CLSTN1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Calsyntenin 1 (CLSTN1) (AA 35-84) antibodyCLSTN1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Fledermaus, Affe, Schwein WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Calsyntenin 1 (CLSTN1) (AA 15-42), (N-Term) antibodyCLSTN1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB38737 unconjugated
anti-Calsyntenin 1 (CLSTN1) (AA 29-350) antibodyCLSTN1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- Calsyntenin 1 (CLSTN1)
- Andere Bezeichnung
- CLSTN1 (CLSTN1 Produkte)
- Hintergrund
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Description: Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1-binding. May modulate calcium-mediated postsynaptic signals (By similarity).
Gene: CLSTN1
- Molekulargewicht
- 110 kDa
- Gen-ID
- 22883
- UniProt
- O94985
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