CMTM4 Antikörper (N-Term)

Produktnummer ABIN6260904

Produktdetails anti-CMTM4 Antikörper

Target: CMTM4 (CKLF-Like MARVEL Transmembrane Domain Containing 4 (CMTM4))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CMTM4 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: CMTM4 Antibody detects endogenous levels of total CMTM4.

Homologie: Pig,Zebrafish,Bovine,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CMTM4, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CMTM4

Target: CMTM4 (CKLF-Like MARVEL Transmembrane Domain Containing 4 (CMTM4))

Andere Bezeichnung: CMTM4 (CMTM4 Produkte)

Synonyme: CKLFSF4 antikoerper, Cklfsf4 antikoerper, D19397 antikoerper, ENSMUSG00000051554 antikoerper, Gm9853 antikoerper, RGD1565098 antikoerper, zgc:92853 antikoerper, CKLF like MARVEL transmembrane domain containing 4 antikoerper, CKLF-like MARVEL transmembrane domain containing 4 antikoerper, CMTM4 antikoerper, Cmtm4 antikoerper, cmtm4 antikoerper

Hintergrund:

Description: Acts as a backup for CMTM6 to regulate plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. May protect PD-L1/CD274 from being polyubiquitinated and targeted for degradation.

Gene: CMTM4

Molekulargewicht: 25kDa

Gen-ID: 146223

UniProt: Q8IZR5