CNDP2 Antikörper (C-Term)

Produktnummer ABIN6260907

Produktdetails anti-CNDP2 Antikörper

Target: CNDP2 (CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNDP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: CNDP2 Antibody detects endogenous levels of total CNDP2.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CNDP2, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CNDP2

Target: CNDP2 (CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2))

Andere Bezeichnung: CNDP2 (CNDP2 Produkte)

Synonyme: 0610010E05Rik antikoerper, C76600 antikoerper, Cn2 antikoerper, Dip-2 antikoerper, Pep-1 antikoerper, Pep1 antikoerper, CN2 antikoerper, CPGL antikoerper, HsT2298 antikoerper, PEPA antikoerper, cn2 antikoerper, cpgl antikoerper, darmin-r antikoerper, CNDP2 antikoerper, zgc:92569 antikoerper, wu:fd20d11 antikoerper, wu:fe17f09 antikoerper, cndp2b antikoerper, PEPC1 antikoerper, PEPCase antikoerper, PPC1 antikoerper, PPEPC4 antikoerper, pepc antikoerper, carnosine dipeptidase 2 antikoerper, CNDP dipeptidase 2 (metallopeptidase M20 family) antikoerper, CNDP dipeptidase 2 (metallopeptidase M20 family) S homeolog antikoerper, CNDP dipeptidase 2 (metallopeptidase M20 family) L homeolog antikoerper, phosphoenolpyruvate carboxylase 1 antikoerper, Cndp2 antikoerper, CNDP2 antikoerper, cndp2 antikoerper, cndp2.S antikoerper, cndp2.L antikoerper, pep1 antikoerper

Hintergrund:

Description: Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly (PubMed:19346245). Acts as a functional tumor suppressor in gastric cancer via activation of the mitogen-activated protein kinase (MAPK) pathway. An elevated level of CNDP2 activates the p38 and JNK MAPK pathways to induce cell apoptosis, and a lower level of CNDP2 activates the ERK MAPK pathway to promote cell proliferation (PubMed:24395568). Isoform 2 may play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells (PubMed:17121880). Catalyzes the production of N-lactoyl-amino acids from lactate and amino acids by reverse proteolysis (PubMed:25964343).

Gene: CNDP2

Molekulargewicht: 53kDa

Gen-ID: 55748

UniProt: Q96KP4