CNGA3 Antikörper (N-Term)

Produktnummer ABIN6260908

Produktdetails anti-CNGA3 Antikörper

Target: CNGA3 (Cyclic Nucleotide Gated Channel alpha 3 (CNGA3))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNGA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: CNGA3 Antibody detects endogenous levels of total CNGA3.

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CNGA3, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CNGA3

Target: CNGA3 (Cyclic Nucleotide Gated Channel alpha 3 (CNGA3))

Andere Bezeichnung: CNGA3 (CNGA3 Produkte)

Synonyme: ACHM2 antikoerper, CCNC1 antikoerper, CCNCa antikoerper, CCNCalpha antikoerper, CNCG3 antikoerper, CNG3 antikoerper, CNGA3 antikoerper, cyclic nucleotide gated channel alpha 3 antikoerper, CNGA3 antikoerper, Cnga3 antikoerper

Hintergrund:

Description: Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.

Gene: CNGA3

Molekulargewicht: 79 kDa

Gen-ID: 1261

UniProt: Q16281

Pathways: Phototransduction