Cofilin Antikörper (N-Term)
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- Target Alle Cofilin (CFL1) Antikörper anzeigen
- Cofilin (CFL1) (Cofilin 1 (CFL1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Cofilin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Cofilin Antibody detects endogenous levels of total Cofilin.
- Homologie
- Pig,Bovine,Horse,Sheep,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Cofilin, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product CFL1 Primärantikörper
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anti-Cofilin 1 (CFL1) (AA 1-166) antibody
CFL1 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 1A1 unconjugated
anti-Cofilin 1 (CFL1) antibodyKO Validated CFL1 Reaktivität: Human WB, IF, IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (AA 3-161) antibodyCFL1 Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (pSer3) antibodyCFL1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (AA 70-98) antibodyCFL1 Reaktivität: Human, Maus WB, FACS Wirt: Kaninchen Polyclonal RB23947 unconjugated
anti-Cofilin 1 (CFL1) (AA 1-100) antibodyCFL1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (AA 2-166) antibodyCFL1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (AA 4-144) antibodyCFL1 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (pSer3) antibodyCFL1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (AA 4-32), (N-Term) antibodyCFL1 Reaktivität: Human, Maus WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB20525 unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- Cofilin (CFL1) (Cofilin 1 (CFL1))
- Andere Bezeichnung
- CFL1 (CFL1 Produkte)
- Hintergrund
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Description: Binds to F-actin and exhibits pH -sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (PubMed:11812157, PubMed:15580268, PubMed:21834987, PubMed:23633677). Required for neural tube morphogenesis and neural crest cell migration (By similarity).
Gene: CFL1
- Molekulargewicht
- 19kDa
- Gen-ID
- 1072
- UniProt
- P23528
- Pathways
- Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
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