COPS7A Antikörper (C-Term)
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- Target Alle COPS7A Antikörper anzeigen
- COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser COPS7A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Spezifität
- COPS7A Antibody detects endogenous levels of total COPS7A.
- Homologie
- Pig,Zebrafish,Horse,Sheep,Rabbit,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human COPS7A, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product COPS7A Primärantikörper
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anti-COP9 Signalosome Complex Subunit 7a (COPS7A) (AA 2-275) antibody
COPS7A Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7a (COPS7A) (AA 1-275) antibodyCOPS7A Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7a (COPS7A) (AA 1-275) antibodyCOPS7A Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7a (COPS7A) (AA 237-266), (C-Term) antibodyCOPS7A Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB32335 unconjugated
anti-COP9 Signalosome Complex Subunit 7a (COPS7A) antibodyCOPS7A Reaktivität: Human, Maus, Ratte IF Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7a (COPS7A) (C-Term) antibodyCOPS7A Reaktivität: Human, Maus, Ratte, Affe, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Fledermaus, Huhn, Hamster, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7a (COPS7A) (Middle Region) antibodyCOPS7A Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7a (COPS7A) (AA 244-274), (C-Term) antibodyCOPS7A Reaktivität: Human WB, EIA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))
- Andere Bezeichnung
- COPS7A (COPS7A Produkte)
- Synonyme
- D6Ertd35e antikoerper, CSN7A antikoerper, COP9 signalosome subunit 7A antikoerper, COPS7A antikoerper, Cops7a antikoerper
- Hintergrund
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Description: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
Gene: COPS7A
- Molekulargewicht
- 30 kDa
- Gen-ID
- 50813
- UniProt
- Q9UBW8
- Pathways
- Zellzyklus
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