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Complexin 1 Antikörper (N-Term)

CPLX1 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6261003
  • Target Alle Complexin 1 (CPLX1) Antikörper anzeigen
    Complexin 1 (CPLX1)
    Bindungsspezifität
    • 15
    • 14
    • 8
    • 7
    • 6
    • 6
    • 1
    N-Term
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 49
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 52
    Polyklonal
    Konjugat
    • 14
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Complexin 1 Antikörper ist unkonjugiert
    Applikation
    • 36
    • 22
    • 19
    • 13
    • 13
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    CPLX1 Antibody detects endogenous levels of total CPLX1.
    Homologie
    Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human CPLX1, corresponding to a region within N-terminal amino acids.
    Isotyp
    IgG
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  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    Complexin 1 (CPLX1)
    Andere Bezeichnung
    CPLX1 (CPLX1 Produkte)
    Synonyme
    MGC84299 antikoerper, CPLX1 antikoerper, CPX-I antikoerper, CPX1 antikoerper, 921-S antikoerper, complexin 1 L homeolog antikoerper, complexin 1 antikoerper, cplx1.L antikoerper, CPLX1 antikoerper, cplx1 antikoerper, Cplx1 antikoerper
    Hintergrund

    Description: Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles (PubMed:21785414). Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse (PubMed:21785414). Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. Essential for motor behavior.

    Gene: CPLX1

    Molekulargewicht
    15-20 kDa
    Gen-ID
    10815
    UniProt
    O14810
    Pathways
    Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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