CYR61 Antikörper (Internal Region)
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- Target Alle CYR61 Antikörper anzeigen
- CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CYR61 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Spezifität
- CYR61/CCN1 Antibody detects endogenous levels of total CYR61/CCN1.
- Homologie
- Rabbit
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CYR61/CCN1, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product CYR61 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
- Andere Bezeichnung
- CYR61 (CYR61 Produkte)
- Synonyme
- CCN1 antikoerper, GIG1 antikoerper, IGFBP10 antikoerper, ccn1 antikoerper, gig1 antikoerper, Xcyr61 antikoerper, igfbp10 antikoerper, MGC69281 antikoerper, MGC69539 antikoerper, cyr61-l2 antikoerper, zgc:158158 antikoerper, CYR61 antikoerper, AI325051 antikoerper, Igfbp10 antikoerper, cysteine rich angiogenic inducer 61 antikoerper, cysteine-rich, angiogenic inducer, 61 antikoerper, cysteine-rich, angiogenic inducer, 61 like 2 antikoerper, cysteine rich protein 61 antikoerper, cysteine rich angiogenic inducer 61 S homeolog antikoerper, CYR61 antikoerper, Cyr61 antikoerper, cyr61 antikoerper, cyr61l2 antikoerper, cyr61.S antikoerper
- Hintergrund
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Description: Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.
Gene: CYR61
- Molekulargewicht
- 42kDa
- Gen-ID
- 3491
- UniProt
- O00622
- Pathways
- Positive Regulation of Endopeptidase Activity, Growth Factor Binding
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