DAAM1 Antikörper (Internal Region)
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- Target Alle DAAM1 Antikörper anzeigen
- DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DAAM1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Spezifität
- DAAM1 Antibody detects endogenous levels of total DAAM1.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human DAAM1, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product DAAM1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))
- Andere Bezeichnung
- DAAM1 (DAAM1 Produkte)
- Synonyme
- 1700066F09Rik antikoerper, 2310028E21Rik antikoerper, AI503486 antikoerper, E130308H01 antikoerper, mKIAA0666 antikoerper, daam-1 antikoerper, xdaam1 antikoerper, daam1 antikoerper, DAAM1 antikoerper, DKFZp468D0524 antikoerper, daam1l antikoerper, fc83b10 antikoerper, si:ch211-87i20.1 antikoerper, wu:fc83b10 antikoerper, dishevelled associated activator of morphogenesis 1 antikoerper, dishevelled associated activator of morphogenesis 1 S homeolog antikoerper, dishevelled associated activator of morphogenesis 1a antikoerper, dishevelled associated activator of morphogenesis 1b antikoerper, DAAM1 antikoerper, Daam1 antikoerper, daam1.S antikoerper, daam1a antikoerper, daam1 antikoerper, daam1b antikoerper
- Hintergrund
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Description: Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments. Involved in building functional cilia (PubMed:16630611, PubMed:17482208). Involved in the organization of the subapical actin network in multiciliated epithelial cells (By similarity). Together with DAAM2, required for myocardial maturation and sarcomere assembly (By similarity).
Gene: DAAM1
- Molekulargewicht
- 123 kDa
- Gen-ID
- 23002
- UniProt
- Q9Y4D1
- Pathways
- WNT Signalweg
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