DMPK Antikörper (N-Term)
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- Target Alle DMPK Antikörper anzeigen
- DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DMPK Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- Spezifität
- DMPK Antibody detects endogenous levels of total DMPK.
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human DMPK, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product DMPK Primärantikörper
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anti-Dystrophia Myotonica-Protein Kinase (DMPK) antibody
DMPK Reaktivität: Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 1-629) antibodyDMPK Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 303-420) antibodyDMPK Reaktivität: Human WB, ELISA, RNAi Wirt: Maus Monoclonal 2F7 unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 243-424) antibodyDMPK Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (N-Term) antibodyDMPK Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (Center) antibodyDMPK Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 323-372) antibodyDMPK Reaktivität: Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Fledermaus WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 1-152) antibodyDMPK Reaktivität: Ratte WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (Middle Region) antibodyDMPK Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Dystrophia Myotonica-Protein Kinase (DMPK) (AA 11-39), (N-Term) antibodyDMPK Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB36813 unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))
- Andere Bezeichnung
- DMPK (DMPK Produkte)
- Hintergrund
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Description: Non-receptor serine/threonine protein kinase which is necessary for the maintenance of skeletal muscle structure and function. May play a role in myocyte differentiation and survival by regulating the integrity of the nuclear envelope and the expression of muscle-specific genes. May also phosphorylate PPP1R12A and inhibit the myosin phosphatase activity to regulate myosin phosphorylation. Also critical to the modulation of cardiac contractility and to the maintenance of proper cardiac conduction activity probably through the regulation of cellular calcium homeostasis. Phosphorylates PLN, a regulator of calcium pumps and may regulate sarcoplasmic reticulum calcium uptake in myocytes. May also phosphorylate FXYD1/PLM which is able to induce chloride currents. May also play a role in synaptic plasticity.
Gene: DMPK
- Molekulargewicht
- 70kDa
- Gen-ID
- 1760
- UniProt
- Q09013
- Pathways
- Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development
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