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DNAJC3 Antikörper (C-Term)

DNAJC3 Reaktivität: Human, Maus, Ratte ELISA, WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6261337
  • Target Alle DNAJC3 Antikörper anzeigen
    DNAJC3 (DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3))
    Bindungsspezifität
    • 15
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 24
    • 18
    • 16
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 37
    • 3
    Kaninchen
    Klonalität
    • 38
    • 2
    Polyklonal
    Konjugat
    • 12
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DNAJC3 Antikörper ist unkonjugiert
    Applikation
    • 14
    • 13
    • 13
    • 10
    • 4
    • 3
    • 3
    • 3
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    DNAJC3 Antibody detects endogenous levels of total DNAJC3.
    Homologie
    Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human DNAJC3, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product DNAJC3 Primärantikörper
  • Applikationshinweise
    WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    DNAJC3 (DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3))
    Andere Bezeichnung
    DNAJC3 (DNAJC3 Produkte)
    Synonyme
    ERdj6 antikoerper, HP58 antikoerper, P58 antikoerper, P58IPK antikoerper, PRKRI antikoerper, zgc:56356 antikoerper, zgc:77731 antikoerper, wu:fb64f06 antikoerper, DNAJC3 antikoerper, dnajc3 antikoerper, DDBDRAFT_0186884 antikoerper, DDBDRAFT_0233602 antikoerper, DDB_0186884 antikoerper, DDB_0233602 antikoerper, cg8286 antikoerper, AA408985 antikoerper, AU067833 antikoerper, Dnajc3a antikoerper, Dnajc3b antikoerper, Prkri antikoerper, mp58 antikoerper, p58 antikoerper, p58IPK antikoerper, fc17a06 antikoerper, prkri antikoerper, wu:fc17a06 antikoerper, DnaJ heat shock protein family (Hsp40) member C3 antikoerper, DnaJ (Hsp40) homolog, subfamily C, member 3a antikoerper, DNAJ heat shock N-terminal domain-containing protein antikoerper, DnaJ heat shock protein family (Hsp40) member C3 L homeolog antikoerper, DnaJ (Hsp40) homolog, subfamily C, member 3b antikoerper, DNAJC3 antikoerper, dnajc3a antikoerper, dnajc3 antikoerper, dnajc3.L antikoerper, Dnajc3 antikoerper, dnajc3b antikoerper
    Hintergrund

    Description: Involved in the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Acts as a negative regulator of the EIF2AK4/GCN2 kinase activity by preventing the phosphorylation of eIF-2-alpha at 'Ser-52' and hence attenuating general protein synthesis under ER stress, hypothermic and amino acid starving stress conditions (By similarity). Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.

    Gene: DNAJC3

    Molekulargewicht
    54 kDa
    Gen-ID
    5611
    UniProt
    Q13217
    Pathways
    ER-Nucleus Signaling
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