DOCK11 Antikörper (Internal Region)

Produktnummer ABIN6261346

Produktdetails anti-DOCK11 Antikörper

Target: DOCK11 (Dedicator of Cytokinesis 11 (DOCK11))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DOCK11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: DOCK11 Antibody detects endogenous levels of total DOCK11.

Homologie: Pig,Zebrafish,Bovine,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DOCK11, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu DOCK11

Target: DOCK11 (Dedicator of Cytokinesis 11 (DOCK11))

Andere Bezeichnung: DOCK11 (DOCK11 Produkte)

Synonyme: ACG antikoerper, ZIZ2 antikoerper, bB128O4.1 antikoerper, 5033414A21Rik antikoerper, 8030476J24 antikoerper, Zizimin2 antikoerper, sph238 antikoerper, dedicator of cytokinesis 11 antikoerper, DOCK11 antikoerper, Dock11 antikoerper

Hintergrund:

Description: Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Required for marginal zone (MZ) B-cell development, is associated with early bone marrow B-cell development, MZ B-cell formation, MZ B-cell number and marginal metallophilic macrophages morphology. Facilitates filopodia formation through the activation of CDC42.

Gene: DOCK11

Molekulargewicht: 238kDa

Gen-ID: 139818

UniProt: Q5JSL3