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DOCK7 Antikörper (N-Term)

DOCK7 Reaktivität: Human, Ratte, Maus ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6261348
  • Target Alle DOCK7 Antikörper anzeigen
    DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))
    Bindungsspezifität
    • 15
    • 5
    • 2
    • 2
    • 2
    N-Term
    Reaktivität
    • 35
    • 16
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Ratte, Maus
    Wirt
    • 33
    • 2
    Kaninchen
    Klonalität
    • 35
    Polyklonal
    Konjugat
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DOCK7 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 9
    • 7
    • 5
    • 3
    • 3
    • 1
    ELISA, Western Blotting (WB)
    Spezifität
    DOCK7 Antibody detects endogenous levels of total DOCK7.
    Homologie
    Pig,Bovine,Sheep,Rabbit,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human DOCK7, corresponding to a region within N-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product DOCK7 Primärantikörper
  • Applikationshinweise
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))
    Andere Bezeichnung
    DOCK7 (DOCK7 Produkte)
    Synonyme
    im:7145816 antikoerper, im:7157388 antikoerper, wu:fb93h07 antikoerper, ZIR2 antikoerper, 3110056M06Rik antikoerper, Gm430 antikoerper, m antikoerper, mKIAA1771 antikoerper, dedicator of cytokinesis 7 antikoerper, dedicator of cytokinesis protein 7 antikoerper, dedicator of cytokinesis 6 antikoerper, DOCK7 antikoerper, dock7 antikoerper, NAEGRDRAFT_56982 antikoerper, LOC100185115 antikoerper, dock6 antikoerper, Dock7 antikoerper
    Hintergrund

    Description: Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation, negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3 (By similarity).

    Gene: DOCK7

    Molekulargewicht
    242kDa
    Gen-ID
    85440
    UniProt
    Q96N67
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