EEF2K Antikörper (Internal Region)

Produktnummer ABIN6261444

Produktdetails anti-EEF2K Antikörper

Target: EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EEF2K Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: EEF2K Antibody detects endogenous levels of total eEF2K.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human eEF2K, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Referenzen für anti-EEF2K Antikörper (ABIN6261444)

Deng, Luo, Lai, Song, Peng, Wei: "Myostatin inhibits eEF2K-eEF2 by regulating AMPK to suppress protein synthesis." in: Biochemical and biophysical research communications, Vol. 494, Issue 1-2, pp. 278-284, (2017) (PubMed).

Details zu EEF2K

Target: EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))

Andere Bezeichnung: EEF2K (EEF2K Produkte)

Synonyme: HSU93850 antikoerper, eEF-2K antikoerper, C86191 antikoerper, SMEF2K antikoerper, eEF-2 kinase antikoerper, cb365 antikoerper, fa04b08 antikoerper, wu:fa04b08 antikoerper, zgc:100973 antikoerper, eukaryotic elongation factor 2 kinase antikoerper, eukaryotic elongation factor-2 kinase antikoerper, EEF2K antikoerper, Eef2k antikoerper, eef2k antikoerper, LOC101930123 antikoerper

Hintergrund:

Description: Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.

Gene: EEF2K

Molekulargewicht: 82kDa

Gen-ID: 29904

UniProt: O00418

Pathways: AMPK Signaling