EHD1 Antikörper (C-Term)

Produktnummer ABIN6261469

Produktdetails anti-EHD1 Antikörper

Target: EHD1 (EH-Domain Containing 1 (EHD1))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EHD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: EHD1 Antibody detects endogenous levels of total EHD1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human EHD1, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu EHD1

Target: EHD1 (EH-Domain Containing 1 (EHD1))

Andere Bezeichnung: EHD1 (EHD1 Produkte)

Synonyme: AA409636 antikoerper, Past1 antikoerper, RME-1 antikoerper, RGD1306960 antikoerper, cb862 antikoerper, ehd1 antikoerper, ehd3 antikoerper, ehd3l antikoerper, wu:fb95h05 antikoerper, zgc:92331 antikoerper, MGC130676 antikoerper, Testilin antikoerper, H-PAST antikoerper, HPAST1 antikoerper, PAST antikoerper, PAST1 antikoerper, zgc:77049 antikoerper, EH-domain containing 1 antikoerper, EH-domain containing 1b antikoerper, EH domain containing 1 L homeolog antikoerper, EH domain-containing protein 1 antikoerper, EH domain containing 1 antikoerper, EH-domain containing 1a antikoerper, Ehd1 antikoerper, ehd1b antikoerper, ehd1.L antikoerper, EHD1 antikoerper, LOC585665 antikoerper, LOC100091823 antikoerper, ehd1a antikoerper

Hintergrund:

Description: ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes vesiculation of endocytic membranes (PubMed:24019528). Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes (PubMed:15020713, PubMed:17233914, PubMed:20801876). Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth (By similarity). Plays a role in myoblast fusion (By similarity). Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing (By similarity). Plays a role in the formation of the ciliary vesicle (CV), an early step in cilium biogenesis. Proposed to be required for the fusion of distal appendage vesicles (DAVs) to form the CV by recruiting SNARE complex component SNAP29. Is required for recruitment of transition zone proteins CEP290, RPGRIP1L, TMEM67 and B9D2, and of IFT20 following DAV reorganization before Rab8-dependent ciliary membrane extension. Required for the loss of CCP110 form the mother centriole essential for the maturation of the basal body during ciliogenesis (PubMed:25686250).

Gene: EHD1

Molekulargewicht: 61 kDa

Gen-ID: 10938

UniProt: Q9H4M9

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development