EHMT2 Antikörper (N-Term)

Produktnummer ABIN6261470

Produktdetails anti-EHMT2 Antikörper

Target: EHMT2 (Ankyrin Repeat-Containing Protein (EHMT2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EHMT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: EHMT2 Antibody detects endogenous levels of total EHMT2.

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human EHMT2, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu EHMT2

Target: EHMT2 (Ankyrin Repeat-Containing Protein (EHMT2))

Andere Bezeichnung: EHMT2 (EHMT2 Produkte)

Synonyme: BAT8 antikoerper, C6orf30 antikoerper, G9A antikoerper, GAT8 antikoerper, KMT1C antikoerper, NG36 antikoerper, T27C4.12 antikoerper, T27C4_12 antikoerper, DL3235W antikoerper, FCAALL.188 antikoerper, T18B16.120 antikoerper, T18B16_120 antikoerper, F9H3.13 antikoerper, F9H3_13 antikoerper, F9H3.7 antikoerper, F9H3_7 antikoerper, F9H3.9 antikoerper, F9H3_9 antikoerper, F9H3.6 antikoerper, F9H3_6 antikoerper, F13G24.40 antikoerper, T20K14.110 antikoerper, T20K14_110 antikoerper, MWD22.10 antikoerper, MWD22_10 antikoerper, MRB17.12 antikoerper, MRB17_12 antikoerper, MAF19.22 antikoerper, MAF19_22 antikoerper, Bat8 antikoerper, D17Ertd710e antikoerper, G9a antikoerper, Ng36 antikoerper, euchromatic histone lysine methyltransferase 2 antikoerper, ankyrin repeat-containing protein antikoerper, Ankyrin repeat family protein antikoerper, euchromatic histone lysine N-methyltransferase 2 antikoerper, EHMT2 antikoerper, ank1 antikoerper, IscW_ISCW006888 antikoerper, Arnit_2917 antikoerper, AT3G04470 antikoerper, AT4G14390 antikoerper, AT4G19150 antikoerper, AT4G03500 antikoerper, AT4G03450 antikoerper, AT4G03460 antikoerper, AT4G03440 antikoerper, PIA1 antikoerper, AT5G15500 antikoerper, AT5G51160 antikoerper, AT5G54620 antikoerper, ANK6 antikoerper, AT1G04780 antikoerper, AT1G62050 antikoerper, Ehmt2 antikoerper

Hintergrund:

Description: Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also mediates monomethylation of 'Lys-56' of histone H3 (H3K56me1) in G1 phase, leading to promote interaction between histone H3 and PCNA and regulating DNA replication. Also weakly methylates 'Lys-27' of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltransferase activity is not required for DNA methylation, suggesting that these 2 activities function independently. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. May also methylate histone H1. In addition to the histone methyltransferase activity, also methylates non-histone proteins: mediates dimethylation of 'Lys-373' of p53/TP53. Also methylates CDYL, WIZ, ACIN1, DNMT1, HDAC1, ERCC6, KLF12 and itself.

Gene: EHMT2

Molekulargewicht: 132kDa

Gen-ID: 10919

UniProt: Q96KQ7