Ephrin B3 Antikörper (Internal Region)

Produktnummer ABIN6261572

Produktdetails anti-Ephrin B3 Antikörper

Target: Ephrin B3 (EFNB3)

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ephrin B3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Ephrin-B3 Antibody detects endogenous levels of total Ephrin-B3.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Ephrin-B3, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu Ephrin B3

Target: Ephrin B3 (EFNB3)

Andere Bezeichnung: EFNB3 (EFNB3 Produkte)

Synonyme: efnb3-A antikoerper, EphB3 antikoerper, EFNB3 antikoerper, efnb3 antikoerper, id:ibd5049 antikoerper, zgc:111938 antikoerper, EFL-6 antikoerper, ELF-3 antikoerper, Elk-L3 antikoerper, Epl8 antikoerper, LERK-8 antikoerper, NLERK-2 antikoerper, ELK-L3 antikoerper, RGD1565678 antikoerper, EFL6 antikoerper, EPLG8 antikoerper, LERK8 antikoerper, ephrin B3 antikoerper, ephrin-B3 L homeolog antikoerper, ephrin-B3b antikoerper, ephrin-B3 antikoerper, EFNB3 antikoerper, efnb3.L antikoerper, efnb3b antikoerper, efnb3 antikoerper, Efnb3 antikoerper

Hintergrund:

Description: Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity).

Gene: EFNB3

Molekulargewicht: 36kDa

Gen-ID: 1949

UniProt: Q15768

Pathways: RTK Signalweg