EXT1 Antikörper

Produktnummer ABIN6261628

Produktdetails anti-EXT1 Antikörper

Target: EXT1 (Exostosin 1 (EXT1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EXT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: EXT1 Antibody detects endogenous levels of total EXT1

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human EXT1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu EXT1

Target: EXT1 (Exostosin 1 (EXT1))

Andere Bezeichnung: EXT1 (EXT1 Produkte)

Synonyme: EXT antikoerper, LGCR antikoerper, LGS antikoerper, TRPS2 antikoerper, TTV antikoerper, AA409028 antikoerper, xext1 antikoerper, fd07d06 antikoerper, wu:fd07d06 antikoerper, exostosin glycosyltransferase 1 antikoerper, exostoses (multiple) 1 antikoerper, exostosin glycosyltransferase 1b antikoerper, exostosin like glycosyltransferase 1 antikoerper, exostosin glycosyltransferase 1 S homeolog antikoerper, exostosin glycosyltransferase 1a antikoerper, EXT1 antikoerper, Ext1 antikoerper, ext1b antikoerper, EXTL1 antikoerper, ext1.S antikoerper, ext1a antikoerper

Hintergrund:

Description: Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413).

Gene: EXT1

Molekulargewicht: 86kDa

Gen-ID: 2131

UniProt: Q16394

Pathways: Glycosaminoglycan Metabolic Process