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FADD Antikörper (N-Term)

FADD Reaktivität: Human WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6261657
  • Target Alle FADD Antikörper anzeigen
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    Bindungsspezifität
    • 17
    • 15
    • 14
    • 8
    • 8
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 92
    • 61
    • 23
    • 19
    • 15
    Human
    Wirt
    • 96
    • 19
    Kaninchen
    Klonalität
    • 94
    • 21
    Polyklonal
    Konjugat
    • 61
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FADD Antikörper ist unkonjugiert
    Applikation
    • 84
    • 47
    • 30
    • 15
    • 15
    • 11
    • 11
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    FADD Antibody detects endogenous levels of total FADD.
    Homologie
    Bovine,Sheep
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human FADD, corresponding to a region within N-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product FADD Primärantikörper
  • Applikationshinweise
    WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    Andere Bezeichnung
    FADD (FADD Produkte)
    Synonyme
    MORT1 antikoerper, Mort1/FADD antikoerper, Mort1 antikoerper, TNFRSF6 antikoerper, adaptor antikoerper, fadd antikoerper, mort1 antikoerper, xfadd antikoerper, Fas associated via death domain antikoerper, Fas (TNFRSF6)-associated via death domain antikoerper, Fas associated via death domain S homeolog antikoerper, Fas (tnfrsf6)-associated via death domain antikoerper, FADD antikoerper, Fadd antikoerper, fadd.S antikoerper, fadd antikoerper
    Hintergrund

    Description: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.

    Gene: FADD

    Molekulargewicht
    28 kDa
    Gen-ID
    8772
    UniProt
    Q13158
    Pathways
    Apoptose, TLR Signalweg, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
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