Frataxin Antikörper (Internal Region)
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- Target Alle Frataxin (FXN) Antikörper anzeigen
- Frataxin (FXN)
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Frataxin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Spezifität
- FXN Antibody detects endogenous levels of total FXN.
- Homologie
- Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human FXN, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product FXN Primärantikörper
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anti-Frataxin (FXN) (AA 57-210) antibody
FXN Reaktivität: Human WB, IHC, StM Wirt: Maus Monoclonal FXN-2124 unconjugated
anti-Frataxin (FXN) (AA 42-210) antibodyFXN Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Frataxin (FXN) (AA 72-102) antibodyFXN Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB12541 unconjugated
anti-Frataxin (FXN) (AA 143-172), (C-Term) antibodyFXN Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB12571 unconjugated
anti-Frataxin (FXN) (AA 91-200) antibodyFXN Reaktivität: Human WB, ELISA, IP Wirt: Maus Monoclonal 1D9 unconjugated
anti-Frataxin (FXN) (AA 91-200) antibodyFXN Reaktivität: Human WB, ELISA, RNAi Wirt: Maus Monoclonal 3G9 unconjugated
anti-Frataxin (FXN) (AA 41-207) antibodyFXN Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Frataxin (FXN) (AA 36-64), (N-Term) antibodyFXN Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB41914 unconjugated
anti-Frataxin (FXN) antibodyFXN Reaktivität: Human, Maus, Ratte IF Wirt: Kaninchen Polyclonal unconjugated
anti-Frataxin (FXN) (AA 1-210) antibodyFXN Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- Frataxin (FXN)
- Andere Bezeichnung
- FXN (FXN Produkte)
- Hintergrund
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Description: Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization, however, the physiological relevance is unsure as reports are conflicting and the function has only been shown using heterologous overexpression systems. Modulates the RNA-binding activity of ACO1.
Gene: FXN
- Molekulargewicht
- 23kDa
- Gen-ID
- 2395
- UniProt
- Q16595
- Pathways
- Transition Metal Ion Homeostasis, Regulation of Cell Size
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