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GANP Antikörper (C-Term)

MCM3AP Reaktivität: Human, Maus WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6261878
  • Target Alle GANP (MCM3AP) Antikörper anzeigen
    GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))
    Bindungsspezifität
    • 15
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 40
    • 13
    • 2
    • 1
    • 1
    Human, Maus
    Wirt
    • 38
    • 2
    Kaninchen
    Klonalität
    • 38
    • 2
    Polyklonal
    Konjugat
    • 15
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GANP Antikörper ist unkonjugiert
    Applikation
    • 26
    • 13
    • 13
    • 13
    • 7
    • 6
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    GANP Antibody detects endogenous levels of total GANP.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human GANP, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
  • Applikationshinweise
    WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))
    Andere Bezeichnung
    MCM3AP (MCM3AP Produkte)
    Synonyme
    GANP antikoerper, MAP80 antikoerper, SAC3 antikoerper, mKIAA0572 antikoerper, minichromosome maintenance complex component 3 associated protein antikoerper, germinal-center associated nuclear protein antikoerper, Mcm3ap antikoerper, MCM3AP antikoerper, mcm3ap antikoerper, LOC100026233 antikoerper
    Hintergrund

    Description: Isoform GANP: Essential for the generation of high-affinity B-cells against T-cell-dependent antigens by affecting somatic hypermutation at the IgV-regions. May have stimulation-dependent DNA primase activity that would generate extra RNA primers in very rapidely proliferating cells and would support clonal expansion of differentiating B-cells (By similarity). Involved in the nuclear export of poly(A)-containing mRNAs by acting as a scaffold for the TREX-2 complex. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.

    Gene: MCM3AP

    Molekulargewicht
    218kDa
    Gen-ID
    8888
    UniProt
    O60318
    Pathways
    Protein targeting to Nucleus
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