GGT1 Antikörper (N-Term)

Produktnummer ABIN6261947

Produktdetails anti-GGT1 Antikörper

Target: GGT1 (gamma Glutamyltransferase 1 (GGT1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GGT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: GGT1 Antibody detects endogenous levels of total GGT1.

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GGT1, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu GGT1

Target: GGT1 (gamma Glutamyltransferase 1 (GGT1))

Andere Bezeichnung: GGT1 (GGT1 Produkte)

Synonyme: ggt1 antikoerper, zgc:64172 antikoerper, CD224 antikoerper, D22S672 antikoerper, D22S732 antikoerper, GGT antikoerper, GGT 1 antikoerper, GTG antikoerper, GGT-1 antikoerper, Ggtp antikoerper, dwg antikoerper, GGLUT antikoerper, Ggt antikoerper, GGT2 antikoerper, cd224 antikoerper, ggt antikoerper, gtg antikoerper, GGT1 antikoerper, ggt1-a antikoerper, gamma-glutamyltransferase 1a antikoerper, gamma-glutamyltransferase 1 antikoerper, gamma-glutamyltranspeptidase 1 antikoerper, gamma-glutamyltransferase 1 L homeolog antikoerper, gamma-glutamyltransferase antikoerper, gamma-glutamyltranspeptidase Ggt1 antikoerper, ggt1a antikoerper, GGT1 antikoerper, Ggt1 antikoerper, ggt1 antikoerper, LOC470168 antikoerper, ggt1.L antikoerper, ggt antikoerper, Bcep18194_A6223 antikoerper, h16_A1098 antikoerper, Shewana3_2487 antikoerper, Bcep1808_2978 antikoerper

Hintergrund:

Description: Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Isoform 3 seems to be inactive.

Gene: GGT1

Molekulargewicht: 60kDa

Gen-ID: 2678

UniProt: P19440