GLI1 Antikörper (C-Term)

Produktnummer ABIN6261968

Produktdetails anti-GLI1 Antikörper

Target: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Gli1 Antibody detects endogenous levels of total Gli1.

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Gli1, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu GLI1

Target: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Andere Bezeichnung: GLI1 (GLI1 Produkte)

Synonyme: GLI antikoerper, Gli antikoerper, Gli-1 antikoerper, gli1.1 antikoerper, AV235269 antikoerper, Zfp-5 antikoerper, Zfp5 antikoerper, GLI family zinc finger 1 antikoerper, GLI family zinc finger 1 S homeolog antikoerper, GLI-Kruppel family member GLI1 antikoerper, GLI1 antikoerper, Gli1 antikoerper, gli1.S antikoerper, gli1 antikoerper

Hintergrund:

Description: Acts as a transcriptional activator (PubMed:19706761, PubMed:10806483, PubMed:19878745, PubMed:24311597, PubMed:24217340). Binds to the DNA consensus sequence 5'-GACCACCCA-3' (PubMed:2105456, PubMed:8378770, PubMed:24217340). May regulate the transcription of specific genes during normal development (PubMed:19706761). May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling (PubMed:19706761). Plays a role in cell proliferation and differentiation via its role in SHH signaling (Probable).

Gene: GLI1

Molekulargewicht: 119 kDa

Gen-ID: 2735

UniProt: P08151

Pathways: Hedgehog Signalweg, Dopaminergic Neurogenesis