GZMB Antikörper
-
- Target Alle GZMB Antikörper anzeigen
- GZMB (Granzyme B (GZMB))
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser GZMB Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Granzyme B antibody detects endogenous levels of total Granzyme B
- Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Granzyme B
- Isotyp
- IgG
- Top Product
- Discover our top product GZMB Primärantikörper
-
-
- Applikationshinweise
- WB: 1:500~1:3000 IHC: 1:50~1:200, IF/ICC 1:100-1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- Haltbarkeit
- 12 months
-
- Target
- GZMB (Granzyme B (GZMB))
- Andere Bezeichnung
- Granzyme B (GZMB Produkte)
- Synonyme
- CCPI antikoerper, CGL-1 antikoerper, CGL1 antikoerper, CSP-B antikoerper, CSPB antikoerper, CTLA1 antikoerper, CTSGL1 antikoerper, HLP antikoerper, SECT antikoerper, granzyme B antikoerper, GZMB antikoerper
- Hintergrund
-
Description: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Gene: GZMB
- Molekulargewicht
- 28kDa
- Gen-ID
- 3002
- UniProt
- P10144, P20718
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose
-