Glutamate Receptor 3 Antikörper

Produktnummer ABIN6262082

Produktdetails anti-Glutamate Receptor 3 Antikörper

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutamate Receptor 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: GRIA3 Antibody detects endogenous levels of total GRIA3

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GRIA3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu Glutamate Receptor 3

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Andere Bezeichnung: GRIA3 (GRIA3 Produkte)

Synonyme: AMPA antikoerper, gria3 antikoerper, GRIN3A antikoerper, glur3b antikoerper, gria3.2 antikoerper, zfGRIA3[b] antikoerper, si:bz1o18.1 antikoerper, SI:zC231H1.1 antikoerper, si:zc140k5.3 antikoerper, GLUR3 antikoerper, GLUR-C antikoerper, GLUR3/C antikoerper, GRIA3 antikoerper, glur3 antikoerper, GluA3 antikoerper, GluR-3 antikoerper, GluR-C antikoerper, GluR-K3 antikoerper, GLUR-K3 antikoerper, GLURC antikoerper, MRX94 antikoerper, 2900064I19Rik antikoerper, Glur-3 antikoerper, Glur3 antikoerper, Gluralpha3 antikoerper, glutamate receptor, ionotropic, AMPA 3b antikoerper, glutamate ionotropic receptor AMPA type subunit 3 antikoerper, glutamate receptor, ionotropic, AMPA 3 antikoerper, glutamate receptor, ionotropic, AMPA 3 L homeolog antikoerper, glutamate receptor, ionotropic, AMPA3 (alpha 3) antikoerper, gria3b antikoerper, GRIA3 antikoerper, gria3 antikoerper, gria3.L antikoerper, Gria3 antikoerper

Hintergrund:

Description: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Gene: GRIA3

Molekulargewicht: 101kDa

Gen-ID: 2892

UniProt: P42263

Pathways: PI3K-Akt Signalweg, cAMP Metabolic Process, Synaptic Membrane