HCFC1 Antikörper (N-Term)
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- Target Alle HCFC1 Antikörper anzeigen
- HCFC1 (Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HCFC1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Spezifität
- HCFC1 Antibody detects endogenous levels of total HCFC1.
- Homologie
- Pig,Bovine,Horse,Rabbit,Dog,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human HCFC1, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product HCFC1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- HCFC1 (Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1))
- Andere Bezeichnung
- HCFC1 (HCFC1 Produkte)
- Synonyme
- CFF antikoerper, HCF-1 antikoerper, HCF1 antikoerper, HFC1 antikoerper, MRX3 antikoerper, VCAF antikoerper, AW060991 antikoerper, HCF antikoerper, RGD1563804 antikoerper, fc61g09 antikoerper, hcfc1 antikoerper, im:7159458 antikoerper, wu:fc61g09 antikoerper, wu:fj40c12 antikoerper, HCFC1 antikoerper, host cell factor C1 antikoerper, host cell factor C1a antikoerper, host cell factor antikoerper, host cell factor C1 (VP16-accessory protein) antikoerper, HCFC1 antikoerper, Hcfc1 antikoerper, hcfc1a antikoerper, LOC5571204 antikoerper, CpipJ_CPIJ014908 antikoerper
- Hintergrund
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Description: Involved in control of the cell cycle (PubMed:10629049, PubMed:10779346, PubMed:15190068, PubMed:16624878, PubMed:23629655). Also antagonizes transactivation by ZBTB17 and GABP2, represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300 (PubMed:10675337, PubMed:12244100). Coactivator for EGR2 and GABP2 (PubMed:12244100, PubMed:14532282). Tethers the chromatin modifying Set1/Ash2 histone H3 'Lys-4' methyltransferase (H3K4me) and Sin3 histone deacetylase (HDAC) complexes (involved in the activation and repression of transcription, respectively) together (PubMed:12670868). Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1 (PubMed:20200153). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852). Recruits KMT2E/MLL5 to E2F1 responsive promoters promoting transcriptional activation and thereby facilitates G1 to S phase transition (PubMed:23629655).
Gene: HCFC1
- Molekulargewicht
- 209kDa
- Gen-ID
- 3054
- UniProt
- P51610
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