HCN2 Antikörper (Internal Region)

Produktnummer ABIN6262168

Produktdetails anti-HCN2 Antikörper

Target: HCN2 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2 (HCN2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HCN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: HCN2 Antibody detects endogenous levels of total HCN2.

Homologie: Pig,Bovine,Sheep,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human HCN2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu HCN2

Target: HCN2 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2 (HCN2))

Andere Bezeichnung: HCN2 (HCN2 Produkte)

Synonyme: HCN2 antikoerper, BCNG-2 antikoerper, BCNG2 antikoerper, HAC-1 antikoerper, HAC1 antikoerper, trls antikoerper, hyperpolarization activated cyclic nucleotide-gated potassium channel 2 antikoerper, hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 antikoerper, hyperpolarization-activated, cyclic nucleotide-gated K+ 2 antikoerper, LOC428335 antikoerper, HCN2 antikoerper, Hcn2 antikoerper

Hintergrund:

Description: Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Can also transport ammonium in the distal nephron. Produces a large instantaneous current. Modulated by intracellular chloride ions and  pH , acidic  pH shifts the activation to more negative voltages (By similarity).

Gene: HCN2

Molekulargewicht: 96 kDa

Gen-ID: 610

UniProt: Q9UL51