HECTD1 Antikörper
-
- Target Alle HECTD1 Antikörper anzeigen
- HECTD1 (HECT Domain Containing 1 (HECTD1))
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser HECTD1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA
- Spezifität
- HECTD1 Antibody detects endogenous levels of total HECTD1
- Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human HECTD1
- Isotyp
- IgG
- Top Product
- Discover our top product HECTD1 Primärantikörper
-
-
- Applikationshinweise
- WB 1:1000-3000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- Haltbarkeit
- 12 months
-
- Target
- HECTD1 (HECT Domain Containing 1 (HECTD1))
- Andere Bezeichnung
- HECTD1 (HECTD1 Produkte)
- Synonyme
- RGD1561653 antikoerper, HECTD1 antikoerper, hectd1 antikoerper, MGC172681 antikoerper, A630086P08Rik antikoerper, AI844876 antikoerper, b2b327Clo antikoerper, opm antikoerper, HECT domain E3 ubiquitin protein ligase 1 antikoerper, HECT domain containing E3 ubiquitin protein ligase 1 antikoerper, Hectd1 antikoerper, HECTD1 antikoerper, hectd1 antikoerper
- Hintergrund
-
Description: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates 'Lys-63'-linked polyubiquitination of HSP90AA1 which leads to its intracellular localization and reduced secretion. Negatively regulating HSP90AA1 secretion in cranial mesenchyme cells may impair their emigration and may be essential for the correct development of the cranial neural folds and neural tube closure.
Gene: HECTD1
- Molekulargewicht
- 289kDa
- Gen-ID
- 25831
- UniProt
- Q9ULT8
- Pathways
- Tube Formation, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion
-