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HIPK1 Antikörper (N-Term)

HIPK1 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6262240
  • Target Alle HIPK1 Antikörper anzeigen
    HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))
    Bindungsspezifität
    • 15
    • 8
    • 8
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 53
    • 27
    • 16
    • 15
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 48
    • 5
    Kaninchen
    Klonalität
    • 49
    • 4
    Polyklonal
    Konjugat
    • 18
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HIPK1 Antikörper ist unkonjugiert
    Applikation
    • 40
    • 24
    • 17
    • 13
    • 13
    • 8
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    Spezifität
    HIPK1 Antibody detects endogenous levels of total HIPK1.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human HIPK1, corresponding to a region within N-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product HIPK1 Primärantikörper
  • Applikationshinweise
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))
    Andere Bezeichnung
    HIPK1 (HIPK1 Produkte)
    Synonyme
    HIPK1 antikoerper, myak antikoerper, nbak2 antikoerper, hipk1 antikoerper, Myak antikoerper, Nbak2 antikoerper, 1110062K04Rik antikoerper, homeodomain interacting protein kinase 1 antikoerper, homeodomain interacting protein kinase 1 L homeolog antikoerper, homeodomain interacting protein kinase 1 S homeolog antikoerper, HIPK1 antikoerper, hipk1.L antikoerper, hipk1 antikoerper, hipk1.S antikoerper, Hipk1 antikoerper
    Hintergrund

    Description: Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis. Plays a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX and MYB. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. Inactivates MYB transcription factor activity by phosphorylation. Prevents MAP3K5-JNK activation in the absence of TNF. TNF triggers its translocation to the cytoplasm in response to stress stimuli, thus activating nuclear MAP3K5-JNK by derepression and promoting apoptosis. May be involved in anti-oxidative stress responses. Involved in the regulation of eye size, lens formation and retinal lamination during late embryogenesis. Promotes angiogenesis and to be involved in erythroid differentiation. May be involved in malignant squamous cell tumor formation.

    Gene: HIPK1

    Molekulargewicht
    131 kDa
    Gen-ID
    204851
    UniProt
    Q86Z02
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