HLA-DMB Antikörper (C-Term)
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- Target Alle HLA-DMB Antikörper anzeigen
- HLA-DMB (Major Histocompatibility Complex, Class II, DM beta (HLA-DMB))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HLA-DMB Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- HLA-DMB Antibody detects endogenous levels of total HLA-DMB.
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human HLA-DMB, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product HLA-DMB Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- HLA-DMB (Major Histocompatibility Complex, Class II, DM beta (HLA-DMB))
- Andere Bezeichnung
- HLA-DMB (HLA-DMB Produkte)
- Synonyme
- RING7 antikoerper, D6S221E antikoerper, RT1.DMb antikoerper, RT1.Mb antikoerper, MHC-DMB antikoerper, major histocompatibility complex, class II, DM beta antikoerper, RT1 class II, locus DMb antikoerper, HLA-DMB antikoerper, RT1-DMb antikoerper, PATR-DMB antikoerper
- Hintergrund
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Description: Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.
Gene: HLA-DMB
- Molekulargewicht
- 29 kDa
- Gen-ID
- 3109
- UniProt
- P28068
- Pathways
- Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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