HMGCR Antikörper (N-Term)

Produktnummer ABIN6262303

Produktdetails anti-HMGCR Antikörper

Target: HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMGCR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: HMGCR Antibody detects endogenous levels of total HMGCR.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human HMGCR, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu HMGCR

Target: HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))

Andere Bezeichnung: HMGCR (HMGCR Produkte)

Synonyme: HMGR antikoerper, LDLCQ3 antikoerper, hmg-coa-r antikoerper, HMG-CoAR antikoerper, Red antikoerper, 3H3M antikoerper, BcDNA:LD15354 antikoerper, CG10367 antikoerper, Clb antikoerper, DmHMG-CoAr antikoerper, Dmel\\CG10367 antikoerper, HMGCR antikoerper, HMGCR_Dm antikoerper, HMGCoAR antikoerper, HMGCoARr antikoerper, HMGCoAr antikoerper, HmG-CoAR antikoerper, Hmg antikoerper, bro1 antikoerper, bs32f05.y1 antikoerper, clb antikoerper, hmgc antikoerper, hmgcr antikoerper, hmgrc antikoerper, l(3)01152 antikoerper, l(3)04684 antikoerper, hmgcr2 antikoerper, im:6912716 antikoerper, zgc:110746 antikoerper, 3-hydroxy-3-methylglutaryl-CoA reductase antikoerper, 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog antikoerper, 3-hydroxy-3-methylglutaryl-Coenzyme A reductase antikoerper, HMG Coenzyme A reductase antikoerper, 3-hydroxy-3-methylglutaryl-CoA reductase b antikoerper, HMGCR antikoerper, hmgcr.L antikoerper, Hmgcr antikoerper, hmgcrb antikoerper

Hintergrund:

Description: Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.

Gene: HMGCR

Molekulargewicht: 95kDa

Gen-ID: 3156

UniProt: P04035

Pathways: AMPK Signaling, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha