HSPE1 Antikörper (Internal Region)

Produktnummer ABIN6262388

Produktdetails anti-HSPE1 Antikörper

Target: HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSPE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: HSP10 Antibody detects endogenous levels of total HSP10.

Homologie: Pig,Zebrafish,Bovine,Horse,Rabbit,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human HSP10, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC: 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu HSPE1

Target: HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))

Andere Bezeichnung: HSPE1 (HSPE1 Produkte)

Synonyme: CPN10 antikoerper, EPF antikoerper, GROES antikoerper, HSP10 antikoerper, groS antikoerper, Cpn10 antikoerper, cpn10 antikoerper, zgc:86747 antikoerper, hspe1 antikoerper, MGC89647 antikoerper, HSPE1 antikoerper, MITOCHONDRIAL CHAPERONIN 10 antikoerper, T15D22.2 antikoerper, T15D22_2 antikoerper, chaperonin 10 antikoerper, Dmel\\CG11267 antikoerper, Hsp10 antikoerper, anon-WO0118547.175 antikoerper, hsp10 antikoerper, crpB antikoerper, chpS antikoerper, 10kDa antikoerper, mt-cpn10 antikoerper, heat shock protein family E (Hsp10) member 1 antikoerper, molecular chaperone GroES antikoerper, chaperonin 10 kDa antikoerper, chaperonin, 10 kDa antikoerper, chaperonin-10 kDa antikoerper, heat shock protein family E member 1 antikoerper, heat shock 10 protein 1 antikoerper, heat shock protein family E (Hsp10) member 1 L homeolog antikoerper, heat shock 10kDa protein 1 (chaperonin 10) pseudogene antikoerper, 10 kd chaperonin antikoerper, chaperonin 10 antikoerper, Hsp10p antikoerper, co-chaperonin 10, mitochondrial antikoerper, CG11267 gene product from transcript CG11267-RA antikoerper, co-chaperonin GroES antikoerper, mitochondrial heat shock protein Hsp10 (predicted) antikoerper, chaperonin GroS antikoerper, Hsp10 10 kDa chaperonin GROES antikoerper, mitochondrial heat shock protein Hsp10 antikoerper, heat shock protein 10 antikoerper, heat shock protein 1 (chaperonin 10) antikoerper, heat shock 10kDa protein 1 (chaperonin 10) antikoerper, HSPE1 antikoerper, groES antikoerper, groES2 antikoerper, TP01_0190 antikoerper, Cag_1167 antikoerper, Bm1_56470 antikoerper, Hspe1 antikoerper, hspe1 antikoerper, hspe1.L antikoerper, LOC452179 antikoerper, Cpn10 antikoerper, CPN10 antikoerper, HSP10 antikoerper, CG11267 antikoerper, hsp10 antikoerper, groS antikoerper

Hintergrund:

Description: Co-chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp60, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix (PubMed:7912672, PubMed:1346131, PubMed:11422376). The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein (Probable).

Gene: HSPE1

Molekulargewicht: 10kDa

Gen-ID: 3336

UniProt: P61604

Pathways: Positive Regulation of Endopeptidase Activity