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EIF3L Antikörper (N-Term)

EIF3L Reaktivität: Human, Maus WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6262447
  • Target Alle EIF3L Antikörper anzeigen
    EIF3L (Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L))
    Bindungsspezifität
    • 15
    • 14
    • 12
    • 2
    • 2
    • 1
    • 1
    N-Term
    Reaktivität
    • 39
    • 30
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 50
    Kaninchen
    Klonalität
    • 50
    Polyklonal
    Konjugat
    • 19
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EIF3L Antikörper ist unkonjugiert
    Applikation
    • 27
    • 19
    • 13
    • 13
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    IF3EI Antibody detects endogenous levels of total IF3EI.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human IF3EI, corresponding to a region within N-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product EIF3L Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    EIF3L (Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L))
    Andere Bezeichnung
    EIF3L (EIF3L Produkte)
    Synonyme
    wu:fb66c05 antikoerper, zgc:64147 antikoerper, EIF3EIP antikoerper, EIF3S11 antikoerper, EIF3S6IP antikoerper, HSPC021 antikoerper, HSPC025 antikoerper, MSTP005 antikoerper, 0610011H21Rik antikoerper, D15N1e antikoerper, Eif3eip antikoerper, Eif3ip antikoerper, Eif3s6ip antikoerper, HSP-66Y antikoerper, PAF67 antikoerper, eif3eip antikoerper, eif3s6ip antikoerper, eukaryotic translation initiation factor 3, subunit 6 interacting protein antikoerper, eukaryotic translation initiation factor 3 subunit L antikoerper, eukaryotic translation initiation factor 3, subunit L antikoerper, eukaryotic translation initiation factor 3 subunit L L homeolog antikoerper, eif3s6ip antikoerper, EIF3L antikoerper, Eif3l antikoerper, eif3l.L antikoerper
    Hintergrund

    Description: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).

    Gene: EIF3L

    Molekulargewicht
    67kDa
    Gen-ID
    51386
    UniProt
    Q9Y262
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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