IGHG1 Antikörper
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- Target Alle IGHG1 Antikörper anzeigen
- IGHG1 (Immunoglobulin Heavy Constant gamma 1 (G1m Marker) (IGHG1))
- Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IGHG1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- IGHG1 Antibody detects endogenous levels of total IGHG1
- Kreuzreaktivität
- Human
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human IGHG1
- Isotyp
- IgG
- Top Product
- Discover our top product IGHG1 Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- Haltbarkeit
- 12 months
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- Target
- IGHG1 (Immunoglobulin Heavy Constant gamma 1 (G1m Marker) (IGHG1))
- Andere Bezeichnung
- IGHG1 (IGHG1 Produkte)
- Synonyme
- RGD1359539 antikoerper, IgG1 antikoerper, Igh-4 antikoerper, VH7183 antikoerper, immunoglobulin heavy constant gamma 1 antikoerper, immunoglobulin heavy constant gamma 1 (G1m marker) antikoerper, Ighg1 antikoerper, IGHG1 antikoerper
- Hintergrund
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Description: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Gene: IGHG1
- UniProt
- P01857
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