CABLES1 Antikörper (C-Term)

Produktnummer ABIN6262503

Produktdetails anti-CABLES1 Antikörper

Target: CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CABLES1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Ik3-1 Antibody detects endogenous levels of total Ik3-1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Ik3-1, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CABLES1

Target: CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))

Andere Bezeichnung: CABLES1 (CABLES1 Produkte)

Synonyme: CABLES1 antikoerper, si:dkey-2p18.3 antikoerper, CABL1 antikoerper, CABLES antikoerper, HsT2563 antikoerper, IK3-1 antikoerper, Cables antikoerper, ik3-1 antikoerper, Cdk5 and Abl enzyme substrate 1 antikoerper, CDK5 and Abl enzyme substrate 1 antikoerper, CABLES1 antikoerper, cables1 antikoerper, CpipJ_CPIJ019832 antikoerper, Cables1 antikoerper

Hintergrund:

Description: Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity).

Gene: CABLES1

Molekulargewicht: 67 kDa

Gen-ID: 91768

UniProt: Q8TDN4