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Importin 5 Antikörper

IPO5 Reaktivität: Human, Ratte, Maus WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6262636
  • Target Alle Importin 5 (IPO5) Antikörper anzeigen
    Importin 5 (IPO5)
    Reaktivität
    • 26
    • 25
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 37
    • 4
    Kaninchen
    Klonalität
    • 39
    • 2
    Polyklonal
    Konjugat
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Importin 5 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 11
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Spezifität
    IPO5 Antibody detects endogenous levels of total IPO5
    Kreuzreaktivität
    Human, Maus, Ratte (Rattus)
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human IPO5
    Isotyp
    IgG
    Top Product
    Discover our top product IPO5 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000 IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C.Stable for 12 months from date of receipt
    Haltbarkeit
    12 months
  • Target
    Importin 5 (IPO5)
    Andere Bezeichnung
    IPO5 (IPO5 Produkte)
    Synonyme
    IPO5 antikoerper, RANBP5 antikoerper, IMB3 antikoerper, KPNB3 antikoerper, Pse1 antikoerper, imp5 antikoerper, 1110011C18Rik antikoerper, 5730478E03Rik antikoerper, AA409333 antikoerper, C76941 antikoerper, Kpnb3 antikoerper, Ranbp5 antikoerper, importin 5 antikoerper, IPO5 antikoerper, Ipo5 antikoerper
    Hintergrund

    Description: Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5. Binds to a beta-like import receptor binding (BIB) domain of RPL23A. In vitro, mediates nuclear import of H2A, H2B, H3 and H4 histones. Binds to CPEB3 and mediates its nuclear import following neuronal stimulation (By similarity). In case of HIV-1 infection, binds and mediates the nuclear import of HIV-1 Rev.

    Gene: IPO5

    Molekulargewicht
    123kDa
    Gen-ID
    3843
    UniProt
    O00410
    Pathways
    Protein targeting to Nucleus
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