ITGA6 Antikörper (N-Term)
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- Target Alle ITGA6 Antikörper anzeigen
- ITGA6 (Integrin, alpha 6 (ITGA6))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ITGA6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Spezifität
- ITGA6 Antibody detects endogenous levels of total ITGA6.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human ITGA6, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product ITGA6 Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- ITGA6 (Integrin, alpha 6 (ITGA6))
- Andere Bezeichnung
- ITGA6 (ITGA6 Produkte)
- Synonyme
- CD49f antikoerper, ITGA6B antikoerper, VLA-6 antikoerper, 5033401O05Rik antikoerper, AI115430 antikoerper, Cd49f antikoerper, ITGA6 antikoerper, inta6 antikoerper, im:6897425 antikoerper, itga6 antikoerper, si:dkey-32o22.1 antikoerper, wu:fb80g02 antikoerper, LOC100221694 antikoerper, si:dkey-18j14.1 antikoerper, wu:fl20e08 antikoerper, zgc:113088 antikoerper, integrin subunit alpha 6 antikoerper, integrin alpha 6 antikoerper, integrin subunit alpha 6 L homeolog antikoerper, integrin, alpha 6a antikoerper, integrin, alpha 6b antikoerper, ITGA6 antikoerper, Itga6 antikoerper, itga6.L antikoerper, itga6a antikoerper, itga6b antikoerper
- Hintergrund
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Description: Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760). ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling (PubMed:28873464).
Gene: ITGA6
- Molekulargewicht
- 127 kDa
- Gen-ID
- 3655
- UniProt
- P23229
- Pathways
- CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
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