JAK1 Antikörper
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- Target Alle JAK1 Antikörper anzeigen
- JAK1 (Janus Kinase 1 (JAK1))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser JAK1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- JAK1 Antibody detects endogenous levels of total JAK1
- Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human JAK1
- Isotyp
- IgG
- Top Product
- Discover our top product JAK1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- Haltbarkeit
- 12 months
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Combination of gemcitabine and erlotinib inhibits recurrent pancreatic cancer growth in mice via the JAK-STAT pathway." in: Oncology reports, Vol. 39, Issue 3, pp. 1081-1089, (2018) (PubMed).
: "BCL2L10 inhibits growth and metastasis of hepatocellular carcinoma both in vitro and in vivo." in: Molecular carcinogenesis, Vol. 56, Issue 3, pp. 1137-1149, (2017) (PubMed).
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Combination of gemcitabine and erlotinib inhibits recurrent pancreatic cancer growth in mice via the JAK-STAT pathway." in: Oncology reports, Vol. 39, Issue 3, pp. 1081-1089, (2018) (PubMed).
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- Target
- JAK1 (Janus Kinase 1 (JAK1))
- Andere Bezeichnung
- JAK1 (JAK1 Produkte)
- Synonyme
- JAK1A antikoerper, JAK1B antikoerper, JTK3 antikoerper, AA960307 antikoerper, C130039L05Rik antikoerper, wu:fb93e10 antikoerper, jak1 antikoerper, Janus kinase 1 antikoerper, tyrosine-protein kinase JAK1 antikoerper, JAK1 antikoerper, Jak1 antikoerper, jak1 antikoerper, LOC100286690 antikoerper
- Hintergrund
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Description: Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway (PubMed:7615558). Kinase partner for the interleukin (IL)-2 receptor (PubMed:11909529).
Gene: JAK1
- Molekulargewicht
- 130kDa
- Gen-ID
- 3716
- UniProt
- P23458
- Pathways
- JAK-STAT Signalweg, RTK Signalweg, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response
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