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FERMT2 Antikörper (C-Term)

FERMT2 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6262815
  • Target Alle FERMT2 Antikörper anzeigen
    FERMT2 (Fermitin Family Member 2 (FERMT2))
    Bindungsspezifität
    • 15
    • 14
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 49
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 39
    • 10
    Kaninchen
    Klonalität
    • 39
    • 10
    Polyklonal
    Konjugat
    • 21
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FERMT2 Antikörper ist unkonjugiert
    Applikation
    • 44
    • 22
    • 13
    • 13
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    Kindlin 2 Antibody detects endogenous levels of total Kindlin 2.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human Kindlin 2, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product FERMT2 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    FERMT2 (Fermitin Family Member 2 (FERMT2))
    Andere Bezeichnung
    FERMT2 (FERMT2 Produkte)
    Synonyme
    AA960555 antikoerper, Kindlin-2 antikoerper, Mig2 antikoerper, Plekhc1 antikoerper, KIND2 antikoerper, MIG2 antikoerper, PLEKHC1 antikoerper, UNC112 antikoerper, UNC112B antikoerper, mig-2 antikoerper, fermitin family member 2 antikoerper, Fermt2 antikoerper, FERMT2 antikoerper
    Hintergrund

    Description: Scaffolding protein that enhances integrin activation mediated by TLN1 and/or TLN2, but activates integrins only weakly by itself. Binds to membranes enriched in phosphoinositides. Enhances integrin-mediated cell adhesion onto the extracellular matrix and cell spreading, this requires both its ability to interact with integrins and with phospholipid membranes. Required for the assembly of focal adhesions. Participates in the connection between extracellular matrix adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits FBLIM1 to focal adhesions. Plays a role in the TGFB1 and integrin signaling pathways. Stabilizes active CTNNB1 and plays a role in the regulation of transcription mediated by CTNNB1 and TCF7L2/TCF4 and in Wnt signaling.

    Gene: FERMT2

    Molekulargewicht
    78 kDa
    Gen-ID
    10979
    UniProt
    Q96AC1
    Pathways
    Cell-Cell Junction Organization
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