KLHL3 Antikörper (N-Term)
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- Target Alle KLHL3 Antikörper anzeigen
- KLHL3 (Kelch-Like 3 (KLHL3))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KLHL3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- KLHL3 Antibody detects endogenous levels of total KLHL3.
- Homologie
- Bovine,Horse,Sheep,Rabbit
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human KLHL3, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product KLHL3 Primärantikörper
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anti-Kelch-Like 3 (KLHL3) (N-Term) antibody
KLHL3 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (AA 1-301) antibodyKLHL3 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (AA 71-120) antibodyKLHL3 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund, Kaninchen, Pferd, Fledermaus, Schwein, Affe WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (AA 51-160) antibodyKLHL3 Reaktivität: Human WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (AA 207-234) antibodyKLHL3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB37267 unconjugated
anti-Kelch-Like 3 (KLHL3) antibodyKLHL3 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (AA 1-301) antibodyKLHL3 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (AA 1-110) antibodyKLHL3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (N-Term) antibodyKLHL3 Reaktivität: Human, Rind (Kuh), Meerschweinchen, Kaninchen, Fledermaus WB Wirt: Kaninchen Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (C-Term) antibodyKLHL3 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund, Pferd, Schwein, Affe WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- KLHL3 (Kelch-Like 3 (KLHL3))
- Andere Bezeichnung
- KLHL3 (KLHL3 Produkte)
- Synonyme
- 7530408C15Rik antikoerper, AI430941 antikoerper, EG627648 antikoerper, PHA2D antikoerper, RGD1565218 antikoerper, kelch like family member 3 antikoerper, kelch-like 3 antikoerper, kelch-like family member 3 antikoerper, KLHL3 antikoerper, Klhl3 antikoerper
- Hintergrund
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Description: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron (PubMed:14528312, PubMed:22406640, PubMed:23387299, PubMed:23453970, PubMed:23576762, PubMed:23665031). The BCR(KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1, leading to WNK4 degradation (PubMed:23387299, PubMed:23453970, PubMed:23576762, PubMed:23665031). The BCR(KLHL3) complex also mediates ubiquitination and degradation of CLDN8, a tight-junction protein required for paracellular chloride transport in the kidney (By similarity).
Gene: KLHL3
- Molekulargewicht
- 64 kDa
- Gen-ID
- 26249
- UniProt
- Q9UH77
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