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LRPPRC Antikörper (Internal Region)

LRPPRC Reaktivität: Human, Maus, Ratte WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6263011
  • Target Alle LRPPRC Antikörper anzeigen
    LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))
    Bindungsspezifität
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 39
    • 28
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 39
    Kaninchen
    Klonalität
    • 39
    Polyklonal
    Konjugat
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LRPPRC Antikörper ist unkonjugiert
    Applikation
    • 28
    • 13
    • 7
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    LRPPRC Antibody detects endogenous levels of total LRPPRC.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human LRPPRC, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product LRPPRC Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))
    Andere Bezeichnung
    LRPPRC (LRPPRC Produkte)
    Synonyme
    CLONE-23970 antikoerper, GP130 antikoerper, LRP130 antikoerper, LSFC antikoerper, Lrp157 antikoerper, 3110001K13Rik antikoerper, C76645 antikoerper, Gp130 antikoerper, Lrp130 antikoerper, Lsfc antikoerper, leucine rich pentatricopeptide repeat containing antikoerper, leucine-rich pentatricopeptide repeat containing antikoerper, leucine-rich PPR-motif containing antikoerper, LRPPRC antikoerper, Lrpprc antikoerper
    Hintergrund

    Description: May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA (By similarity).

    Gene: LRPPRC

    Molekulargewicht
    130 kDa
    Gen-ID
    10128
    UniProt
    P42704
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