MBD2 Antikörper (Internal Region)
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- Target Alle MBD2 Antikörper anzeigen
- MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MBD2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- MBD2 Antibody detects endogenous levels of total MBD2.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MBD2, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product MBD2 Primärantikörper
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anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (Internal Region) antibody
Verified MBD2 Reaktivität: Human WB, ELISA, IHC Wirt: Ziege Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (AA 250-279) antibodyMBD2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal RB41663 unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (N-Term) antibodyMBD2 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (AA 145-411) antibodyMBD2 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (AA 10-228) antibodyMBD2 Reaktivität: Human WB, IHC (p) Wirt: Maus Monoclonal 1812CT625-9-45 unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (AA 120-151), (AA 120-152) antibodyMBD2 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB3952 unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (AA 202-411) antibodyMBD2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) antibodyMBD2 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (Middle Region) antibodyMBD2 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (Center) antibodyMBD2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
- Andere Bezeichnung
- MBD2 (MBD2 Produkte)
- Synonyme
- MBD2 antikoerper, DMTase antikoerper, NY-CO-41 antikoerper, MBD2a antikoerper, wu:fa97f06 antikoerper, zgc:111862 antikoerper, methyl-CpG binding domain protein 2 antikoerper, methyl-CpG binding domain protein 2 S homeolog antikoerper, MBD2 antikoerper, Mbd2 antikoerper, mbd2 antikoerper, mbd2.S antikoerper
- Hintergrund
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Description: Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.
Gene: MBD2
- Molekulargewicht
- 43 kDa
- Gen-ID
- 8932
- UniProt
- Q9UBB5
- Pathways
- Chromatin Binding
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