MCM10 Antikörper (C-Term)

Produktnummer ABIN6263157

Produktdetails anti-MCM10 Antikörper

Target: MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCM10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: MCM10 Antibody detects endogenous levels of total MCM10.

Homologie: Pig,Zebrafish,Horse,Sheep,Rabbit,Dog,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MCM10, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu MCM10

Target: MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))

Andere Bezeichnung: MCM10 (MCM10 Produkte)

Synonyme: CG9241 antikoerper, DmMCM10 antikoerper, Dmel\\CG9241 antikoerper, Scim19 antikoerper, mcm10 antikoerper, CNA43 antikoerper, DNA43 antikoerper, xmcm10 antikoerper, 2410041F14Rik antikoerper, AU018508 antikoerper, C330019M07Rik antikoerper, C79164 antikoerper, Minichromosome maintenance 10 antikoerper, minichromosome maintenance 10 replication initiation factor antikoerper, minichromosome maintenance 10 replication initiation factor L homeolog antikoerper, Mcm10 antikoerper, MCM10 antikoerper, mcm10.L antikoerper

Hintergrund:

Description: Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Additionally, plays a role in preventing DNA damage during replication. Key effector of the RBBP6 and ZBTB38-mediated regulation of DNA-replication and common fragile sites stability, acts as a direct target of transcriptional repression by ZBTB38 (PubMed:24726359).

Gene: MCM10

Molekulargewicht: 97-105 kDa

Gen-ID: 55388

UniProt: Q7L590

Pathways: Mitotic G1-G1/S Phases, DNA Replication